BIX 02189 - Names and Identifiers
BIX 02189 - Physico-chemical Properties
Molecular Formula | C27H28N4O2
|
Molar Mass | 440.54 |
Storage Condition | -20℃ |
Use | A MEK5 and ERK5 catalytic activity blocker. |
BIX 02189 - Introduction
BIX 02189 is a selective MEK5 inhibitor. IC50 is 1.5 nM and also inhibits ERK5 catalytic activity. IC50 is 810 nM and does not inhibit its closely related kinases MEK1, MEK2, ERK2, and JNK2.
Last Update:2022-10-16 17:24:19